PLANTING THE SEEDS FOR A FOREST OF RNAI PATHWAYS

Planting the seeds for a forest of RNAi pathways

Cells from most eukaryotic species make several different types of small interfering RNAs.Pioneering work in plants, published in PLOS Biology almost 20 years ago, established a framework to understand how multiple toyo proxes st iii 305/40r22 RNA interference pathways can regulate the genome in parallel.This Perspective looks back at a classic PLO

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Roots of Design Futures in art, architecture, and design

Design Futures is herewith proposed and discussed as a conceptualization of existing methodological streams in corporate design history, in the analysis of Italian Design Districts, and fenway park collection hats in other creative industry fields, inspiring a fundamental tension to anticipate what will come next, which artists, architects and desi

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UNESCO monographs in the making of cultural policy

Between 1969 and 1987, UNESCO published a series of 77 monographs on aspects related to cultural policies of individual countries.Each monograph mobilized cultural policy in very particular ways, by its association with local issues, jacques marie mage picabia increasing awareness and communication about issues that formerly had never been grouped

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The single-cell transcriptomic atlas iPain identifies senescence of nociceptors as a therapeutical target for chronic pain treatment

Abstract Chronic pain remains a significant medical challenge with complex underlying mechanisms, and an urgent need for new treatments.Our goorara.to research built and utilized the iPain single-cell atlas to study chronic pain progression in dorsal root and trigeminal ganglia.We discovered that senescence of a small subset of pain-sensing neurons

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